BD, or cannabidiol, is quickly changing the debate surrounding the use of marijuana as a medicine.
A great many people have known about a compound called THC, which is the fixing in cannabis that gets clients high. Be that as it may, as of late, consideration has moved to another compound in weed called CBD — and in light of current circumstances.
Since while specialists can’t look past certain reactions of THC, CBD doesn’t seem to present that issue. Then again, confirmation of CBD’s health advantages keeps on developing.
Here are five certainties that you ought to think about this interesting compound:
1. CBD is a key ingredient in cannabis
CBD is one of more than 60 compounds found in cannabis that have a place with a class of particles called cannabinoids. Of these compounds, CBD and THC are normally present in the most noteworthy cannabinoids, and are subsequently the most perceived and examined.
CBD and THC levels have a tendency to fluctuate among various plants. Cannabis developed for recreational purposes regularly contains more THC than CBD.
Be that as it may, by utilizing particular rearing procedures, cannabis reproducers have figured out how to make assortments with abnormal amounts of CBD and alongside zero levels of THC. These strains are uncommon yet have turned out to be more prominent as of late.
2. CBD is non-psychoactive
Unlike THC, CBD does not cause a high. While this makes CBD a poor choice for recreational users, it gives the chemical a significant advantage as a medicine, since health professionals prefer treatments with minimal side effects.
CBD is non-psychoactive because it does not act on the same pathways as THC. These pathways, called CB1 receptors, are highly concentrated in the brain and are responsible for the mind-altering effects of THC.
A 2011 review published in Current Drug Safety concludes that CBD “does not interfere with several psychomotor and psychological functions.” The authors add that several studies suggest that CBD is “well tolerated and safe” even at high doses.
3. CBD has a wide range of medical benefits
Although CBD and THC act on different pathways of the body, they seem to have many of the same medical benefits. According to a 2013 review published in the British Journal of Clinical Pharmacology, studies have found CBD to possess the following medical properties:
|Medical Properties of CBD||Effects|
|Antiemetic||Reduces nausea and vomiting|
|Anticonvulsant||Suppresses seizure activity|
|Antipsychotic||Combats psychosis disorders|
|Anti-inflammatory||Combats inflammatory disorders|
|Anti-oxidant||Combats neurodegenerative disorders|
|Anti-tumoral/Anti-cancer||Combats tumor and cancer cells|
|Anxiolytic/Anti-depressant||Combats anxiety and depression disorders|
Unfortunately, most of this evidence comes from animals, since very few studies on CBD have been carried out in human patients.
But a pharmaceutical version of CBD was recently developed by a drug company based in the UK. The company, GW Pharmaceuticals, is now funding clinical trials on CBD as a treatment for schizophrenia and certain types of epilepsy.
Likewise, a team of researchers at the California Pacific Medical Center, led by Dr. Sean McAllister, has stated that they hope to begin trials on CBD as a breast cancer therapy.
4. CBD reduces the negative effects of THC
CBD seems to offer natural protection against the marijuana high. Numerous studies suggest that CBD acts to reduce the intoxicating effects of THC, such as memory impairment and paranoia.
CBD also appears to counteract the sleep-inducing effects of THC, which may explain why some strains of cannabis are known to increase alertness.
5. CBD is still illegal
On the other hand, the U.S. Food and Drug Administration recently approved a request to trial a pharmaceutical version of CBD in children with rare forms of epilepsy. The drug is made by GW Pharmaceuticals and is called Epidiolex.
According to the company, the drug consists of “more than 98 percent CBD, trace quantities of some other cannabinoids, and zero THC.” GW Pharmaceuticals makes another cannabis-based drug called Sativex, which has been approved in over 24 countries for treating multiple sclerosis.
A patent awarded to the U.S. Health and Human Services in 2003 (US6630507) also covers the use of CBD as a treatment for various neurodegenerative and inflammatory disorders.